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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Jun 19;34(8):1723–1730. doi: 10.1161/ATVBAHA.114.303983

Figure 2.

Figure 2

Carotid arteries from LDLR−/− mice following wire injury. Compared to sham-transplanted control (A), transplanted wild-type (wt) PVAT resulted in a robust neointimal response (NI, panel B). Note that the transplanted adipocytes are healthy appearing and in intimate contact with the lamina adventitia. Transplanted MCP-1−/− PVAT was not associated with robust NI formation (C). scale bar = 200µm. (D) Transplanted PVAT increases cross-sectional area of neointimal lesion following wire injury. *p<0.05 PVAT + injury vs. all other groups. Data were analyzed by one-way analysis of variance (ANOVA) followed by pairwise multiple comparison procedures (Holm-Sidak method).