Fig. 1.

Two possible complexes for the design of a ZFN, in “straight” (a) and “reverse” (b) orientations. NColE7 in green and ZF protein consisting of three fingers in orange. The N- and C-termini of the proteins are marked in blue and red, respectively. The proposed links at positions S1, S2, R1 and R2 are indicated in Tables S2 and S3