Figure 4.

(a) Free-energy landscape of coil unzipping obtained by MetaD simulation of the coiled coil, with the CV d₂ defined as the distance between the backbone COM of one strand (say, P₁) from the backbone COM of the two other strands (say, P₂ and P₃). (b) The distance between the COMs of each heptad repeat of strand P₁ from the corresponding heptads of strands P₂ and P₃ as a function of simulation time. To see this figure in color, go online.