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. 2014 Jul 15;107(2):448–459. doi: 10.1016/j.bpj.2014.04.066

Figure 5.

Figure 5

Normalized probability histograms of fitted persistence length values from three methods. Normalized probability histograms of P (along with Gaussian distributions drawn to guide the eye) for natural DNA (solid), diaminopurine substitution (dash), and inosine substitution (dot dash) are shown for the indicated techniques: (A) cyclization, (B) AFM, and (C) force spectroscopy using optical tweezers. For legibility, histograms for cyclization are omitted. Histograms for the AFM data are the result of binning the 10 estimates of P from WLC theory discussed in Section S2 in the Supporting Material. Histograms for the tweezers data come from binning the corrected values from each force-extension curve (∼35 for each construct).