Table 1.
Biophysical properties and concentration ranges
| Human | Yeast | |
|---|---|---|
| pH, cytosol | 7.4a | 7b |
| Redox potential, cytosol | −315 mVc | −286 mVd |
| pH, mitochondria | 7.98a | 7.4b |
| Redox potential, mitochondria | −360 mVe | −296 mVd |
| pH, IMS | 6.7f | 6.3f |
| Redox potential, IMS | −242g | −213d |
| Ionic strength | 0.15 Mb | |
| Oxygen concentration (mM) | [10−4;0.1] | |
| [CO2], [Pi], [Ppi] (mM) | [1;100]b | |
| Other reactants (mM) | [10−4,10]b,h | |
| Adenylate energy charge (AEC) | [10−4,10]b | |
| NADH/NAD ratio | [10−4,10] | |
| NADPH/NADP ratio | [10−4,10] | |
a
Values from Llopis et al. (21).
b
Values from Kummel et al. (15).
c
Values from Björnberg et al. (19).
d
Values from Hu et al. (20).
e
Value from Hanson et al. (23).
f
Values from Porcelli et al. (22), considering 0.7 units lower than cytosolic pH.
g
The variation between redox potential in cytosol and IMS of yeast was used as a reference.
h
Value from Haraldsdóttir et al. (13).