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Signal transduction mechanisms and cell processes that regulate or are associated with the amoeboid phenotype. CSF-1: Colony stimulating factor 1; EGFR: epidermal growth factor receptor; EPC: endothelial progenitor cell; EV: extracellular vesicle; GAP: GTPase-activating protein; GEF: guanine nucleotide exchange factor; IL-6: interleukin-6; MAT: mesenchymal-to-amoeboid transition; PAI: plasminogen activator inhibitor type-1; TGFβ1: transforming growth factor beta 1; TNC: Tenascin C.
