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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Pediatr Res. 2014 May 23;76(2):177–183. doi: 10.1038/pr.2014.76

Table 1.

Plasma concentrations (nmol/L) of 25(OH)D by supplement dose.

Age (mo) Vitamin D supplement dose (IU/day)
200 400 600 800

1 Number of observations 56 60 56 41
Mean ± SD 35.1 ± 18.7 42.2 ± 18.6 43.4 ± 21.0 44.2 ± 19.8
Range 9.8 – 93.5 13.5 – 99.0 12.5 – 97.2 8.2 – 103.0
Number (%) <50 nmol/L 46 (82) 45 (75) 36 (64) 26 (63)
Number (%) <30 25 (45) 19 (32) 18 (32) 10 (24)

2 Number of observ. 53 55 49 37
Mean ± SD 64.3 ± 21.0 72.2 ± 19.5 77.3 ± 21.6 82.7 ± 30.7
Range 13.4 – 140.5 22.2 – 119.2 22.8 – 141.2 34.5 – 195.2
Number (%) <50 13 (24) 4 (7) 4 (8) 3 (8)
Number (%) <30 3 (6) 2 (4) 1 (2) 0

4 Number of observ. 46 44 42 33
Mean ± SD 76.1 ± 28.2 81.3 ± 29.2 101.6 ± 32.4 100.9 ± 27.2
Range 16.2 – 150.8 16.8 – 136.0 45.0 – 209.8 44.8 – 175.5
Number (%) <50 5 (11) 8 (18) 1 (2) 2 (6)
Number (%) <30 2 (4) 3 (7) 0 0

5.5 Number of observ. 45 37 40 30
Mean ± SD 75.1 ± 30.1 84.5 ± 29.9 97.6 ± 27.3 103.0 ± 23.6
Range 7.8 – 153.2 11.8 – 141.0 23.2 – 154.8 50.0 – 163.8
Number (%) <50 5 (11) 5 (14) 2 (5) 0
Number (%) <30 5 (11) 2 (5) 1 (2) 0

7.5 Number of observ. 42 34 32 28
Mean ± SD 85.7 ± 23.9 94.3 ± 29.9 101.6 ± 33.0 115.8 ± 24.8
Range 29.5 – 142.8 7.0–167.8 42.5–180.0 68.5–182.2
Number (%) <50 2 (5) 1 (3) 2 (6) 0
Number (%) <30 1 (2) 1 (3) 0 0

9 Number of observ. 39 31 30 25
Mean ± SD 92.8 ± 20.7 95.2 ± 23.0 103.2 ± 23.4 118.1 ± 27.2
Range 36.0 – 153.5 47.5–134.0 38.5–153.2 74.5–180.2
Number (%) <50 1 (3) 1 (3) 1 (3) 0
Number (%) <30 0 0 0 0

12 Number of observ. 38 30 27 24
Mean ± SD 87.9 ± 24.7 85.1 ± 17.6 81.0 ± 18.4 90.4 ± 16.8
Range 49.0 – 134.5 45.0–118.5 38.2–116.0 57.0–122.5
Number (%) <50 1 (3) 1 (3) 1 (4) 0
Number (%) <30 0 0 0 0