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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Inflamm Bowel Dis. 2014 Aug;20(8):1419–1425. doi: 10.1097/MIB.0000000000000096

Fig. 1. Crohn's disease-associated Escherichia coli (CDEC) strain, 13I invades and replicates in macrophages and epithelial cells.

Fig. 1

(A) J774.A1 macrophages and (B) Caco2 cells were infected for 3 hrs with CD-associated E. coli strains LF82 and 13I, and intracellular CFU was measured by Gentamicin protection assay, and expressed as percentage of initial inoculum (I/O). Non-pathogenic E coli strain, EFC-1 and UC-associated E coli strain, 30A were used as controls. Data are mean ± S.D. Statistical significance was determined by student's t test.