Table 2.
Baseline Characteristics of Youth With Inflammatory Bowel Disease (IBD) and Depression by Psychotherapy Type
| Measure | CBT (n=110) | SNDT (n=107) | Test Statistic (p-value) | ||
|---|---|---|---|---|---|
|
| |||||
| n (%) | Mean (SD) | n (%) | Mean (SD) | ||
|
| |||||
| Demographics | |||||
|
| |||||
| Age | -- | 14.3 (2.5) | -- | 14.3 (2.3) | t=−0.16 (0.87) |
|
| |||||
| Gender (Male) | 54 (49.1) | -- | 48 (44.9) | -- | χ2=0.39 (0.53) |
|
| |||||
| Site (Pittsburgh) | 65 (59.1) | -- | 65 (60.8) | -- | χ2=0.06 (0.80) |
|
| |||||
| Race (White) | 104 (94.6) | -- | 90 (84.1) | -- | χ2=6.23 (0.01)a |
|
| |||||
| SES | -- | 1.3 (0.6) | -- | 1.1 (0.6) | t=1.42 (0.16) |
|
| |||||
| Depression | |||||
|
| |||||
| CDI Child | -- | 12.7 (6.3) | -- | 13.8 (6.7) | t=−1.21 (0.23) |
|
| |||||
| CDI Parent | -- | 14.0 (6.1) | -- | 14.8 (7.3) | t=−0.84 (0.40) |
|
| |||||
| CDRS-R | -- | 45.1 (12.1) | -- | 48.9 (12.8) | t=−2.26 (0.02)a |
|
| |||||
| Major Depression (versus Minor Depression) | 68 (61.8) | -- | 69 (64.5) | -- | χ2=0.17 (0.68) |
|
| |||||
| Health-related Adjustment | |||||
|
| |||||
| CGAS | -- | 58.6 (4.8) | -- | 58.8 (4.6) | t=−0.22 (0.83) |
|
| |||||
| IMPACT-IIIb | -- | 118.9 (20.8) | -- | 113.7 (22.9) | t=1.57 (0.12) |
|
| |||||
| Disease Activity | |||||
|
| |||||
| Months since IBD diagnosis (between diagnosis & screen) | -- | 22.8 (30.4) | -- | 23.7 (28.5) | t=−0.23 (0.82) |
|
| |||||
| PUCAI (ulcerative colitis) | 27 | 23.3 (24.9) | 26 | 25.8 (23.8) | t=−0.36 (0.72) |
|
| |||||
| PCDAI (Crohn’s disease) | 79 | 21.0 (16.2) | 74 | 22.4 (16.9) | t=−0.53 (0.60) |
|
| |||||
| Erythrocyte sedimentation rate | -- | 21.9 (16.1) | -- | 24.3 (19.0) | t=−0.93 (0.35) |
|
| |||||
| C-reactive protein | -- | 1.4 (2.8) | -- | 1.4 (2.1) | t=0.13 (0.90) |
|
| |||||
| IBD Medications | |||||
| Systemic steroids | 27 (24.6) | -- | 28 (26.2) | -- | χ2=0.08 (0.78) |
| Biologics | 27 (24.6) | 34 (31.8) | χ2=1.40 (0.24) | ||
| Immunomodulators | 52 (47.3) | 51 (47.7) | χ2=0.003 (0.95) | ||
|
| |||||
| Surgery (yes versus no) | 6 (5.6) | -- | 15 (14.2) | -- | χ2=4.47 (0.04)a |
|
| |||||
| Ostomy (yes versus no) | 2(1.8) | -- | 6(5.6) | -- | χ2=2.15 (0.14) |
Note: Demographic information is given by portion of whole, where gender is broken down by male and female, site by Pittsburgh v. Boston, and race by white v. black. CBT = cognitive behavioral therapy; CDI = Children’s Depression Inventory; CDRS-R = Children’s Depression Rating Scale-Revised; CGAS = Children’s Global Assessment Scale; PCDAI = Pediatric Crohn’s Disease Activity Index; PUCAI = Pediatric Ulcerative Colitis Activity Index; SES = socioeconomic status; SNDT = supportive non-directive therapy.
a
Indicates statistical significance.
b
IMPACT-III is a health-related quality of life assessment.