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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Behav Brain Res. 2014 Jun 2;0:72–78. doi: 10.1016/j.bbr.2014.05.046

Fig. 2.

Fig. 2

Male and female C57BL/6 Fmr1 knockout mice show significant hyperactivity in the open field test. WT and Fmr1 KO mice at 2 to 3 months of age were placed in an open field arena, and allowed to freely explore for 2 hours. The total movement distance (A), center distance (B), time spent in the center (C), and entry number to the center (D) were scored. Data presented as mean ± SEM were analyzed by three-way (genotype × gender × time) ANOVA with repeated measures. Both male and female mutants are hyperactive than the corresponding WT controls (p < 0.005)