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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Behav Brain Res. 2014 Jun 2;0:72–78. doi: 10.1016/j.bbr.2014.05.046

Fig. 4.

Fig. 4

Male and female C57BL/6 Fmr1 knockout mice show significant deficits in contextual memory. Animals at 2 to 3 months of age were trained by contextual fear conditioning, during which a mild electric foot shock (as indicated by the block arrow in A) was delivered. The ambulatory distance the animals traveled during the 3-min training is shown in A. During the testing (24 hours after training), the percentage of freezing (immobility behavior) was scored (B). Data presented as mean ± SEM were analyzed by two-way ANOVA followed by pairwise comparison analysis, which indicates significant less freezing in both male and female Fmr1 knockout animals comparing to the corresponding WT controls.