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Mediation Analysis to evaluate indirect effect of PRBC on AKI via Biomarkers
| Direct Pathway Estimate C |
Alternate Pathway Estimate |
Mediation Estimate Ć |
Sobel Test |
Mediation Percentage |
P Value for Mediation |
||
|---|---|---|---|---|---|---|---|
| a | b | ||||||
|
Urine IL-18
(pg/ml) |
0.973 | 0.518 | −0.32 | 0.822 | −2.19 | 17.07% | 0.02 |
|
Urine NGAL
(ng/ml) |
0.973 | 0.496 | 0.122 | 0.901 | −1.3 | 6.22% | 0.19 |
Mediation percentage is the percentage of total effect of PRBC transfusion on AKI that is mediated via biomarkers.
