Figure 4.

Topological and spatial properties of the C. elegans nervous system are related: rich club neurons (red triangles) are distinguished from poor periphery neurons (blue circles) on all topological metrics. Rich club neurons tend to have higher degree (by definition), higher efficiency, higher betweenness, and higher participation coefficients than peripheral neurons. The connection distance of each neuron is the average of the physical distances between it and all of the other neurons to which it is synaptically connected in the network. Most rich club neurons have greater connection distance than most peripheral neurons, but some of the neurons with greatest connection distance are in the periphery.