Table 2. Local Maxima of Significant Clusters Showing Decreased Gray Matter Volume in Regular Cannabis Smokers.

Region	Left hemisphere MNI coordinates (mm)			T-value	Cluster extent	Right hemisphere MNI coordinates (mm)			T-value	Cluster extent
	x	y	z			x	y	z
Superior orbital gyrus	−22	14	−14	5.15
Temporal pole	−50	10	−14	5.14		50	14	−20	3.59	213a
Middle temporal gyrus	−56	2	−28	4.84	1215	64	−10	−20	4.36	271
Medial temporal pole	−48	10	−32	4.52		46	14	−34	3.94	213a
Insula lobe	−36	8	−10	4.22
Parahippocampal gyrus	−26	10	−42	3.98	130	24	6	−36	3.62	64
Precuneus						12	−54	16	3.83	85

^aBelong to the same cluster.