Table 2. Social and Nonsocial Cognitive Assessments.

		Placebo			Oxytocin			Effects p<0.05
		Baseline mean (SD) (n=14)	Posttreatment mean (SD) (n=11)	1 month follow up mean (SD) (n=10)	Baseline mean (SD) (n=13)	Posttreatment mean (SD) (n=11)	1 month follow up mean (SD) (n=11)	Time (placebo)	Time (oxytocin)	Time (combined groups)	Oxytocin
PONS	Total (of 110)	81.3 (4.4)	83.1 (7.1)	86.4 (6.7)	79.3 (7.2)	79.2 (8.6)	81.6 (5.6)			p=0.04 at 1 month
TASIT	Total (of 64)	49.5 (6.1)	49.1 (6.4)	51.3 (4.4)	46.1 (6.2)	46.5 (6.5)	47.4 (7.1)
	Lie (of 32)	26.2 (3.6)	25.4 (4.7)	27.1 (3.6)	23.6 (3.7)	23.4 (4.4)	24.3 (4)
	Sarcasm (of 32)	23.2 (4.8)	23.7 (5.4)	24.2 (4.9)	22.5 (5.3)	23.1 (5.8)	23.1 (6.6)
Facial affect recognition	Fraction correct	0.75 (0.1)	0.9 (0.1)	0.91 (0.1)	0.78 (0.1)	0.86 (0.1)	0.84 (0.1)	p<0.0001 posttreatment and at 1 month	p=0.0003 posttreatment and p=0.01 at 1 month	p<0.0001 posttreatment and at 1 month
Empathic accuracy	Total (r)	0.66 (0.2)	0.64 (0.2)	0.65 (0.1)	0.62 (0.2)	0.71 (0.2)	0.7 (0.2)				p=0.03 posttreatment and at 1 month
MSCEIT managing emotions	Score (of 150)	82.2 (14)	91 (17)	89.5 (11)	83.6 (15)	86.2 (18)	87.8 (15)	p=0.02 posttreatment		p=0.01 posttreatment and p=0.03 at 1 month
Social-cognition composite	Z-score	0.035 (0.8)	0.35 (0.8)	0.51 (0.6)	−0.13 (0.8)	0.11 (0.7)	0.29 (0.7)		p=0.05 posttreatment	p=0.03 posttreatment and p<0.01 at 1 month
MCCB nonsocial composite	Z-score	−0.09 (0.6)	0.11 (0.5)	0.41 (0.5)	0.09 (0.8)	0.08 (0.9)	0.16 (1)	p=0.004 at 1 month		p<0.01 at 1 month

Values in the last four columns indicate statistically significant (p<0.05) within-group effects (indicated by placebo or oxytocin), main effects of time (indicated by combined groups) or treatment x-time interactions (in oxytocin column).