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. Author manuscript; available in PMC: 2014 Dec 20.
Published in final edited form as: Stat Med. 2013 Jul 16;32(29):5039–5052. doi: 10.1002/sim.5902

Table IV.

Validation.

Configuration Mean Maximum1 Observed p-value
D
Test for signal 2 0.014 0.031 0.055 < 0.001
3 0.028 0.052 0.073 < 0.001
4 0.040 0.065 0.095 < 0.001
5 0.051 0.081 0.114 < 0.001
ΔD
Test for increment 2 versus 3 0.014 0.030 0.017 0.12
2 versus 4 0.026 0.048 0.040 0.01
2 versus 5 0.037 0.065 0.059 0.001
3 versus 4 0.012 0.025 0.022 0.003
3 versus 5 0.023 0.043 0.042 0.001
4 versus 5 0.011 0.024 0.019 0.006
1

Maximum over 2000 simulations.