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. 2014 Jul 21;4:5764. doi: 10.1038/srep05764

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(A) Time course of Whi5P in our CLE model. The experimental data are marked with a star. (B) The time course of a WT yeast cell when no pheromone is added. (C) The time course of a WT yeast cell when pheromone is added at 0 min. (D) Relationship between the addition time of pheromone and the activation of Whi5P. Here we set R = 0, indicating that the intrinsic fluctuations in all the reaction channels are independent of each other.