Table 1.

Neurocognitive Disorders as Diagnosed in DSM-5

Diagnostic Criteria	Major Neurocognitive Disorder/Dementia		Mild Neurocognitive Disorder/MCI
A	Significant cognitive decline in one or more cognitive domains, based on:		Modest cognitive decline in one or more cognitive domains, based on:
	1.	Concern about significant decline, expressed by individual or reliable informant, or observed by clinician.	1.	Concern about mild decline, expressed by individual or reliable informant, or observed by clinician.
	2.	Substantial impairment, documented by objective cognitive assessment.	2.	Modest impairment, documented by objective cognitive assessment.
B	Interference with independence in everyday activities.		No interference with independence in everyday activities, although these activities may require more time and effort, accommodation, or compensatory strategies
C	Not exclusively during delirium.
D	Not better explained by another mental disorder.
E	Specify one or more etiologic subtypes, “due to”
	Alzheimer’s disease Cerebrovascular disease (Vascular Neurocognitive Disorder) Frontotemporal Lobar Degeneration (Frontotemporal Neurocognitive Disorder) Dementia with Lewy Bodies (Neurocognitive Disorder with Lewy Bodies) Parkinson’s disease Huntington’s disease Traumatic Brain Injury HIV Infection Prion Disease Another medical condition Multiple etiologies

Adapted from: American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Arlington, VA, American Psychiatric Association; 2013