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. Author manuscript; available in PMC: 2014 Jul 21.
Published in final edited form as: Cell Host Microbe. 2013 May 15;13(5):613–623. doi: 10.1016/j.chom.2013.04.011

Figure 6. HIV-responsive SR-proteins regulate HIV-1 splicing and virion release.

Figure 6

(A) Lysates from depleted MAGI cells were analyzed by immunoblot with each antibody. (B) Relative quantification of HIV-1 transcripts. Band intensities of tat and nef alternatively spliced products (top panel) were divided by tat-1 and nef-2, respectively for quantification (bottom panel). n=6 (C) HIV-1 release following depletion of SR proteins as measured by p24 collected on day 5 post infection. Comparisons were made between each SRRM2 siRNA and the non-targeting control siRNA. Bars=SEM, n=4, *p<0.05, **p<0.01 Mann-Whitney, ns: not significant (p>0.05). See also Figure S3.