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. Author manuscript; available in PMC: 2014 Jul 21.
Published in final edited form as: J Urol. 2012 Oct 8;189(3):1130–1136. doi: 10.1016/j.juro.2012.08.222

Table 4.

Changes of urothelium, collagen, and smooth muscle areas in the bladder.

Tissue cross-sectional area (mm2) Percentage of the total tissue
cross-sectional area (%)
Total Collagen Muscle Urothelium Collagen Muscle Urothelium
Control 9.83±0.50 3.55±0.13 4.10±0.17 0.65±0.06 36.4±2.3 41.9±1.7 6.7±0.6
Sham 8.64±0.91 3.45±0.25 3.63±0.26 0.52±0.06 40.3±1.3 42.5±1.9 6.1±0.3
DIU 13.10±1.00a 3.96±0.23 6.30±0.59a 0.96±0.09a 30.6±1.2c 48.0±1.6 7.4±0.7
DM 14.34±0.52a 4.07±0.24 6.75±0.29a 1.10±0.13a 28.4±1.6c 47.1±1.7 7.6±0.7
UD 6.46±0.40b 3.18±0.27 1.92±0.11b 0.22±0.03b 49.2±2.9b 30.0±1.7b 3.3±0.4b
UD+DM 6.10±0.28b 3.14±0.17 1.93±0.07b 0.18±0.01b 51.5±1.8b 31.8±0.9b 2.9±0.2b

Values are expressed as means plus or minus standard error of the mean of 6 individual rats.

a

significantly different from corresponding value in control, sham, UD and UD+DM groups (P <0.01).

b

significantly different from corresponding value in control, sham, DM, and DIU groups (P <0.01)

c

significantly different from corresponding value in sham, UD and UD+DM groups (P <0.01).

Abbreviations: DIU, 5% sucrose-induced diuretics after sham urinary diversion; DM, diabetes mellitus; UD, urinary diversion.