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. Author manuscript; available in PMC: 2014 Jul 21.
Published in final edited form as: Neuropharmacology. 2012 Mar 15;69:75–81. doi: 10.1016/j.neuropharm.2012.03.005

Fig 2. Modulation of EPSP integration by HCN and KV7/M- channel inhibitors.

Fig 2

A Example recordings showing the effects of the HCN channel inhibitor, ZD7288 (ZD, 15 μM) and the KV7/M- channel blocker, XE991 (3 μM) on entorhinal cortical (EC) dendritic αEPSP summation and hippocampal dendritic αEPSP integration respectively. αEPSPs were obtained by current injection of the alpha waveform (for methods see (Shah, Anderson et al. 2004). B Traces demonstrating the effects of ZD7288 and XE991 on αEPSP summation in EC and hippocampal soma respectively. The figure has been adapted from (Shah, Anderson et al. 2004) and (Shah, Migliore et al. 2011).