Table 2.

Effect of methanolic extract of P. integrifolia bark on Open Field test in rats

Group	Dose	Number of Movements
		0 min	30 min	60 min	90 min	120 min
Group-I	10ml/kg	12.8 ± 1.15	13 ± 1.41	13.6 ± 0.92	14.2 ± 0.86	14 ± 0.54
Group-II	1mg/kg	11.2 ± 0.58	6 ± 0.70*	4 ± 0.83*	2.4±0.81*	1.8±0.37*
Group-III	100 mg/kg,	12 ± 0.70	7.8 ± 0.58*	5.4±0.50*	4.2±0.37*	3.2±0.37*
Group-IV	200 mg/kg,	12.2 ± 0.66	6.2 ± 0.37*	4 ± 0.70*	2.8±0.37*	1.4±0.40*

Values are mean±SEM, (n=6);

^* p<0.05, Dunnet test as compared to vehicle control. Group I animals received vehicle (1% tween 80 in water), group II received diazepam 1 mg/kg body weight, group III and group IV were treated with 100 and 200 mg/kg body weight (p.o.) of the MEPI.