Table 3.

Effect of methanolic extract of P. integrifolia bark on acetic acid induced writhing in rats

Groups	Dose	No. of writhing	%inhibition
Group-I	0.1 ml/10gm	26.33 ± 0.55
Group-II	10mg/kg	10.83 ± 1.22*	58.8
Group-III	100mg/kg	13.0 ± 1.69*	50.63
Group-IV	200mg/kg	10.33 ± 0.76*	60.75

Values are mean±SEM, (n=5);

^* p<0.05, Dunnet test as compared to vehicle control. Group I animals received vehicle (1% tween 80 in water), group II received diclofenac Na 10 mg/kg body weight, group III and group IV were treated with 100 and 200 mg/kg body weight (p.o.) of the MEPI.