Table 4.

Effect of methanolic extract of P. integrifolia bark in hindpaw licking in the formalin test in rats

Groups	Dose	Early phase (Sec)	% protection	Late phase (Sec)	% protection
Group-I	10 ml/kg,	35.67 ± 1.38	-	46.0 ± 1.03	-
Group-II	10 mg/kg,	16.83 ± 0.90*	52.8	21.83 ± 0.70*	52.53
Group-III	100 mg/kg,	27.5 ± 0.76*	22.89	21.5 ± 0.95*	53.26
Group-IV	200mg/kg	16.17 ± 0.65*	54.67	18.0 ± 1.46*	60.86

Values are mean±SEM, (n=5);

^* p<0.05, Dunnet test as compared to vehicle control. Group I animals received vehicle (1% tween 80 in water), group II received diclofenac Na 10 mg/kg body weight, group III and group IV were treated with 100 and 200 mg/kg body weight (p.o.) of the MEPI.