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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Metabolism. 2014 Mar 15;63(6):773–782. doi: 10.1016/j.metabol.2014.03.008

Table 2.

Correlations between liver function tests, fetuin-A and baseline values of study variables

ALT
GGT
AST
Fetuin-A
Model 1
Model 2
Model 1
Model 2
Model 1
Model 2
Model 1
Model 2
r P r P r P r P r P r P r P r P
Age 0.01 0.74 −0.02 0.61 0.11 0.01 −0.04 0.31
Activity −0.02 0.67 −0.03 0.44 −0.03 0.47 0.02 0.70
Smoking status 0.06 0.16 0.13 0.001 0.02 0.58 −0.03 0.53
Anthropometrics
Height 0.06 0.12 −0.04 0.34 0.02 0.70 0.05 0.22
Weight 0.44 <.0001 0.39 <.0001 0.09 0.02 0.15 0.0002
BMI 0.46 <.0001 0.45 <.0001 0.10 0.02 0.15 0.0004
Total body fat 0.46 <.0001 0.46 <.0001 0.10 0.01 0.14 0.0009
Fat mass 0.47 <.0001 0.44 <.0001 0.10 0.01 0.13 0.001
Fat free mass 0.36 <.0001 0.03 0.44 0.30 <.0001 −0.08 0.06 0.08 0.06 0.03 0.51 0.15 0.0003 0.06 0.16
Waist circumference 0.47 <.0001 0.45 <.0001 0.11 0.006 0.16 <.0001
Hip circumference 0.41 <.0001 0.39 <.0001 0.18 0.06 0.16 <.0001
WHR 0.39 <.0001 0.40 <.0001 0.13 0.001 0.11 0.010
BMR 0.42 <.0001 0.05 0.21 0.36 <.0001 −0.07 0.08 0.09 0.03 0.03 0.53 0.15 0.0003 0.05 0.23
Cardiovascular risk factors
Heart rate 0.22 <.0001 0.14 0.0003 0.15 0.0003 0.06 0.13 0.04 0.29 0.01 0.75 0.04 0.39 0.01 0.73
SBP 0.31 <.0001 0.10 0.015 0.29 <.0001 0.08 0.06 0.05 0.21 0.003 0.95 0.12 0.004 0.04 0.30
DBP 0.14 0.0004 −0.001 0.97 0.12 0.002 −0.01 0.76 0.03 0.47 −0.01 0.81 0.07 0.08 0.03 0.54
Total cholesterol 0.32 <.0001 0.19 <.0001 0.35 <.0001 0.24 <.0001 0.08 0.04 0.04 0.32 0.06 0.12 0.03 0.40
HDL −0.03 0.50 0.08 0.04 −0.07 0.07 0.04 0.33 0.01 0.74 0.04 0.28 −0.02 0.71 0.02 0.61
LDL 0.34 <.0001 0.21 <.0001 0.38 <.0001 0.26 <.0001 0.07 0.06 0.04 0.38 0.10 0.02 0.07 0.11
Triglycerides 0.19 <.0001 −0.002 0.95 0.31 <.0001 0.13 0.001 −0.01 0.76 −0.06 0.13 0.04 0.28 −0.005 0.91
Dyslipidemia 0.18 <.0001 0.05 0.18 0.17 <.0001 0.04 0.33 0.02 0.70 −0.01 0.74 0.01 0.74 −0.02 0.62
Hormonal and metabolic variables
Fasting glucose 0.13 0.001 0.01 0.77 0.14 0.0003 0.04 0.30 0.02 0.60 −0.003 0.93 0.01 0.74 −0.03 0.53
Insulin 0.37 <.0001 0.17 <.0001 0.30 <.0001 0.09 0.02 0.07 0.09 0.02 0.62 0.15 0.0002 0.08 0.07
HOMA-IR 0.36 <.0001 0.16 0.0001 0.30 <.0001 0.09 0.02 0.07 0.10 0.02 0.63 0.14 0.0005 0.06 0.12
Leptin* 0.41 <.0001 0.04 0.31 0.46 <.0001 0.15 0.0002 0.07 0.09 −0.03 0.43 0.10 0.012 −0.02 0.54
LBP −0.16 <.0001 0.06 0.14 −0.21 <.0001 −0.002 0.97 −0.02 0.56 0.03 0.48 −0.08 0.06 −0.01 0.88
Uric acid 0.13 0.001 0.05 0.26 0.14 0.0003 0.06 0.14 0.06 0.13 0.04 0.27 0.02 0.56 0.001 0.99
Urea −0.02 0.60 0.02 0.59 −0.04 0.35 0.002 0.95 0.08 0.06 0.09 0.03 0.01 0.87 0.03 0.50
Creatinine −0.05 0.19 −0.03 0.45 −0.05 0.24 −0.02 0.62 0.02 0.67 0.02 0.55 −0.05 0.26 −0.04 0.35
Liver function tests
ALT 0.54 <.0001 0.41 <.0001 0.52 <.0001 0.53 <.0001 0.11 0.006 0.06 0.13
GGT 0.54 <.0001 0.42 <.0001 0.11 0.008 0.06 0.13 0.15 0.0002 0.10 0.02
AST 0.52 <.0001 0.53 <.0001 0.11 0.01 0.06 0.13 −0.005 0.91 −0.02 0.69
*

Values of leptin were logarithmically transformed for analysis.

Model 1: Pearson correlation coefficients and the probabilities associated with this statistics.

Model 2: Pearson partial correlation coefficients were obtained after controlling for the effects of age, smoking status, activity, BMI, body fat percentage, and WHR.

P<0.0125 was considered statistically significant based on Bonferroni correction testing four dependent hypotheses at same time on one set of data.

ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BMR, basal metabolic rate; DBP, Diastolic blood pressure; GGT, gamma-glutamyl transferase; HDL, High-density lipoprotein; HOMA-IR, homeostasis model of assessment-insulin resistance; LBP, leptin-binding protein; LDL, Low-density lipoprotein; SBP, Systolic blood pressure; WHR, waist-to-hip ratio.