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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Virology. 2013 Dec 5;449:140–149. doi: 10.1016/j.virol.2013.10.037

Table 1.

Infectivity of SIV Vif N-Terminal Mutants

Vif ΔVif K5A R6A R14A R18A R21A H23A K27A K30A K32A K34A K38A K46A
RhA3A 100a 7* 86 44 90 47 44 76 86 100 78 46 93 88
RhA3B 100 100 79 80 66 100 76 100 100 100 100 95 100 100
RhA3C 100 91 100 63 60 100 53 100 100 100 48 70 70 62
RhA3D 100 2* 57 24* 0.7* 36 18* 48 100 66 75 35 92 93
RhA3F 100 7* 99 37 21* 100 14* 11* 19* 23* 13* 16* 100 84
RhA3G 100 4* 100 61 0.1* 100 57 77 1.0* 102 80 62 100 100
RhA3H 100 22* 65 100 1.0* 93 37 16* 79 25* 100 14* 98 70
a

Infectivity of virus expressing the unmodified Vif was considered 100%. Those values that were statistically significant are marked with an (*). Infectivity was determined by transfecting 293 cells with the vectors with the viral genome and one expressing one of the rhA3 proteins, collecting virus at 48 h and assaying for infectivity using the TZM.bl assay.