Figure 4. HERV family-specific population diversity of post-burn expressed HERVs among four patients.
Within each HERV family, the diversity of post-burn expressed HERV populations among four patients was measured. Each patient’s HERV population was compared to the HERV populations of the other three or two patients within each HERV family. Individual patients are identified with various symbols. As the distance from the center increases, the relatedness of the indicated HERV populations to the reference HERV population decreases (e.g., Pt1 [patient-1] vs. Pt2, Pt4, and Pt11). Within the HERV-FRD, HERV-H(1), and HERV-K5 families, the expressed HERV populations were relatively diverse among the four patients in comparison to the other families, such as HERV-E, HERV-K2, and HERV-K4. HERV-H(1) and HERV-H(2) were derived from two RT-PCR amplicons of HERV-H. HERV-K1, HERV-K6, HERV-L and RRHERV-I were examined only in three patient groups. RR-I (RRHERV-I).