Table 5.
Reference | Patients | AUC | Sensitivity (%) |
Specificity (%) |
Cut-off (ng/mL) |
Assay | Source | |
---|---|---|---|---|---|---|---|---|
Mishra et al.82 | 25 | Children | – | – | – | – | NGAL staining | Biopsies |
Parikh et al.83 | 53 | Adults + children |
0.90 | 90 | 83 | >1000 ng/mg creatinine |
ELISA (Antibody Shop) |
Urine |
Lebkowska et al.84 | 41 | Adults | 0.99 | 100 | 85 | – | ELISA (Antibody Shop) |
Blood |
Hall et al.85 | 91 | Adults | 0.81 | 77 | 74 | >350 | ELISA (Antibody Shop) |
Urine |
Hollmen et al.86 | 176 | Adults | 0.75 | 68 | 73 | >560 | Standardized Clinical Platform (ARCHITECT®) |
Urine |
Hollmen et al.87 | 275 | Adults | 0.60 | 34.8 | 79.4 | >20 | Standardized Clinical Platform (ARCHITECT®) |
Urine and blooc |
Kusaka et al.88 | 67 | Adults | 0.99 | 91 | 97 | >500 | Standardized Clinical Platform (ARCHITECT®) |
Blood |
Bataille et al.89 | 41 | Adults | 0.97 | 93.3 | 88.5 | >400 | Triage®point of care device | Blood |
Magnusson et al.90 | 111 | Adults | – | – | – | – | ELISA (Antibody Shop) |
Blood |
Heyne et al.91 | 182 | Adults | 0.98 | 100 | 93 | >100 | ELISA (Antibody Shop) |
Urine |
Lee et al.92 | 59 | Adults | 0.86 | 78.6 | 77.8 | >233 | ELISA (Antibody Shop) |
Blood |
Rahimzadeh et al.93 | 27 | Children | 0.95 | 100 | 95.5 | >175 | ELISA (not specified) |
Blood + urine |
Rostami et al.94 | 64 | Adults | 0.71 | 72 | 67 | 204 | ELISA (Antibody Shop) |
Urine |
Lee et al.95 | 59 | Adults | 0.86 | 77 | 78 | 233 | ELISA (Antibody Shop) |
Blood |
Total (for DGF) | 1079 | 0.87 | 82 | 83 | – | – | – |