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. Author manuscript; available in PMC: 2015 Jan 28.

Published in final edited form as: J Control Release. 2013 Nov 12;174:88–97. doi: 10.1016/j.jconrel.2013.11.003

Fig 3 — Fraction of TPT retained in DSPC/DSPE-PEG2K liposomes vs. time at varying pH (right panel displays only the first 6 hrs). Release studies were conducted at pH 3.35 , 4.10 , 5.10 +, 5.93 , 6.33 , 7.04 , 7.39 , and 7.67 x. The solid curves of the same color represent the simultaneous fit of the mechanism-based mathematical model developed in this paper to the entire data set.

Inline graphic — Fraction of TPT retained in DSPC/DSPE-PEG2K liposomes vs. time at varying pH (right panel displays only the first 6 hrs). Release studies were conducted at pH 3.35 , 4.10 , 5.10 +, 5.93 , 6.33 , 7.04 , 7.39 , and 7.67 x. The solid curves of the same color represent the simultaneous fit of the mechanism-based mathematical model developed in this paper to the entire data set.