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. 2014 Jul 21;4:94. doi: 10.3389/fcimb.2014.00094

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Copyright © 2014 Bachtiar, Bachtiar, Jarosz, Amir, Sunarto, Ganin, Meijler and Krom.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AI-2 plays a role in biofilm formation of A. actinomyc-etemcomitans. Biofilm formation of A. actinomycetemcomitans luxS is restored to near wild-type levels by the addition of sterile spent medium (left panel) as well as by the addition of 100 nM synthetic DPD (right panel). ^*Indicates significantly different from control.