Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 21;5:325. doi: 10.3389/fimmu.2014.00325

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Krengel and Bousquet.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Example of ganglioside recognition [here: GT1b (analog) and its interaction with botulinum neurotoxin type A (BoNT/A)]. (A) Experimental electron density (Fo–Fc omit map) of the ganglioside head group. (B) Schematic drawing of the interactions between GT1b and BoNT/A. Hydrogen bonds are shown as dotted lines (red: intermolecular interactions; black: intramolecular carbohydrate–carbohydrate interactions). (C) Close-up view of the ligand-binding site. Please note the aromatic stacking interactions with Trp 1266 and Tyr 1117. Printed with permission from Ref. (40).