Table 4. False Positive (Specificity) and False Negative (Sensitivity) of LLRC versus Single Metrics for Velos-Orbitrapa.
metric | LLRC | P_2C | P_2A | MS1_2B |
---|---|---|---|---|
false positive (specificity) | 0.071 (0.929) | 0.323 (0.677) | 0.386 (0.614) | 0.735 (0.265) |
false negative (sensitivity) | 0.066 (0.934) | 0.066 (0.934) | 0.066 (0.934) | 0.066 (0.934) |
The sensitivity is held constant at 0.934 to show the sensitivity for any single metric compared to the LLRC. From Rudnick et al.5 P_2C is the total unique tryptic peptide identifications; P_2A is the total spectrum identifications; MS1_2B is the median TIC.