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. 2014 Mar 10;13(4):2215–2222. doi: 10.1021/pr401143e

Table 4. False Positive (Specificity) and False Negative (Sensitivity) of LLRC versus Single Metrics for Velos-Orbitrapa.

metric LLRC P_2C P_2A MS1_2B
false positive (specificity) 0.071 (0.929) 0.323 (0.677) 0.386 (0.614) 0.735 (0.265)
false negative (sensitivity) 0.066 (0.934) 0.066 (0.934) 0.066 (0.934) 0.066 (0.934)
a

The sensitivity is held constant at 0.934 to show the sensitivity for any single metric compared to the LLRC. From Rudnick et al.5 P_2C is the total unique tryptic peptide identifications; P_2A is the total spectrum identifications; MS1_2B is the median TIC.