Figure 5.
Overall hippocampal presynaptic density and regional uniformity predict place recognition memory. Scatterplots showing correlation between place recognition memory and (A) average hippocampal presynaptic density (p <.001) and (B) coefficient of variation of synaptic densities across five subregions (p = .001). Both features were found to independently predict place memory in a multiple regression analysis. Runners had higher overall hippocampal presynaptic density, less sub-regional variability, and superior memory performance.