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. Author manuscript; available in PMC: 2014 Oct 10.
Published in final edited form as: Nature. 2014 Apr 2;508(7495):199–206. doi: 10.1038/nature13185

Figure 1. Prenatal human brain atlas components.

Figure 1

a. Nissl stained (right) and corresponding annotated reference atlas (left) plate, color coded by structure. b. ISH for RELN showing expression in Cajal-Retzius cells at low (left) and high (right) magnification in MZ. c. High resolution MRI and tract DWI of fixed ex cranio brain. d. Experimental strategy for systematic histology, anatomical delineation and LMD-based isolation of discrete anatomical structures for microarray analysis. Nissl, acetylcholinesterase (AChE) and GAP43 ISH were used to identify structures. e. Quantitative representation of microarray data for FOLR1, TGIF1, and SIX3. GE: ganglionic eminence. See Supplemental Table 2 for other anatomical abbreviations.