Table 2.

Risk of Recurrence by PAM50 Intrinsic Subtype

	All Recurrences n=370				Early Recurrences (<5 years) n=243				Late Recurrences (5-10 years) n=127
PAM50 Subtype	N Events	HR	Lower 95 CI	Upper 95 CI	N Events	HR	Lower 95 CI	Upper 95 CI	N Events	HR	Lower 95 CI	Upper 95 CI
Luminal A	127		ref		61		ref		66		ref
Luminal B	120	1.94	1.36	2.77	82	2.55	1.68	3.88	38	1.34	0.79	2.28
Luminal B PATHWAYS	53	1.54	0.99	2.41	52	2.39	1.48	3.86	1	0.14	0.02	1.08
Luminal B LACE	67	2.42	1.54	3.82	30	2.93	1.67	5.14	37	1.73	0.99	3.04
HER2-E	67	1.63	1.10	2.41	54	2.83	1.83	4.38	13	0.55	0.28	1.09
Basal-like	56	2.10	1.37	3.22	46	3.98	2.47	6.42	10	0.59	0.28	1.23
Basal-like PATHWAYS	33	3.83	2.33	6.28	33	5.44	3.23	9.15	0
Basal-like LACE	23	1.29	0.75	2.23	13	2.41	1.23	4.75	10	0.63	0.30	1.33

^*Adjusted for age, race/ethnicity, tumor size, number of positive nodes and grade