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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Feb 12;23(5):725–734. doi: 10.1158/1055-9965.EPI-13-1017

Table 3.

Risk of Breast Cancer Death by PAM50 Intrinsic Subtype

All BC Deaths n=274 Early BC Deaths (<5 years) n=115 Late BC Deaths (5-10 years) n=154

PAM50 Subtype N Events HR Lower 95 CI Upper 95 CI N Events HR Lower 95 CI Upper 95 CI N Events HR Lower 95 CI Upper 95 CI
Luminal A 96 ref 23 ref 73 Ref
Luminal B 86 1.77 1.16 2.70 35 2.67 1.46 4.88 49 1.47 0.87 2.48
 Luminal B PATHWAYS 29 1.42 0.81 2.47 26 3.01 1.55 5.85 3 0.43 0.12 1.49
 Luminal B LACE 57 2.03 1.23 3.35 9 2.03 0.86 4.81 48 1.74 1.01 3.01
HER2-E 46 1.27 0.79 2.02 24 2.97 1.58 5.59 22 0.73 0.40 1.33
Basal-like 46 1.84 1.12 3.01 33 6.23 3.31 11.73 13 0.61 0.30 1.23
 Basal-like PATHWAYS 25 4.74 2.64 8.51 24 8.60 4.38 16.88 1 0.86 0.11 6.61
 Basal-like LACE 21 1.05 0.58 1.93 9 3.63 1.54 8.56 12 0.59 0.29 1.22
*

Adjusted for age, race/ethnicity, tumor size, number of positive nodes and grade