Table 5.
Spontaneous Awakening and Breathing Trial Implementation
| Mechanically Ventilated Patients |
|||
|---|---|---|---|
| Variable | Pre-ABCDE Bundle N = 93 |
Post-ABCDE Bundle N = 94 |
p-value |
| Received a continuously infused sedative medicationa anytime during ICU stay, n (%) | 67 (72%) | 59 (62.8%) | 0.18 |
| Had continuously infused sedative medicationa held at least once for a spontaneous awakening trial (SAT), n (%) | 35 (53%) | 42 (71.2%) | 0.04 |
| SATs performed on eligible days (sedative medicationa only), median % (IQR) | 42.9 (25, 66.7) | 50 (33.3, 55.6) | 0.38 |
| Received a continuously infused opioid medicationb anytime during ICU stay, n (%) | 34 (36.6%) | 30 (31.9%) | 0.50 |
| Had continuously infused opioid medicationb held at least once for a SAT, n (%) | 15 (45.5%) | 18 (60%) | 0.25 |
| SATs performed on eligible days (opioid medicationb only), median % (IQR) | 25 (14.3, 40) | 50 (45.2, 66.7) | 0.001 |
| Received a continuously infused sedativea or opioidb medication anytime during ICU stay, n (%) | 72 (77.4%) | 66 (70.2%) | 0.26 |
| Had continuously infused sedativea or opioidb medication held at least once for a SAT, n (%) | 36 (50.7%) | 42 (63.6%) | 0.13 |
| SATs performed on eligible days (sedativea or opioidb medication held), median % (IQR) | 33.3 (24.4, 52.8) | 50 (33.3, 50) | 0.18 |
| Underwent a spontaneous breathing trial (SBT) anytime during ICU stay, n (%) | 65 (70.7%) | 79 (84%) | 0.03 |
| SBT/mechanical ventilation days, median (IQR) | 50 (31.8, 66.7) | 50 (33.3, 66.7) | 0.94 |
ICU = intensive care unit; IQR = interquartile range; n = number; SAT = spontaneous awakening trial; SBT = spontaneous breathing trial.
a
Includes the following medications: lorazepam, midazolam, propofol, and dexmedetomidine.
b
Includes the following medications: morphine, hydromorphone, and fentanyl.