Figure 1. Global cortical PiB vs regional FDG.

Age- and sex-adjusted mean FDG within each PiB group for the 47 regions of interest. The regions are sorted by level of significance. The estimates assume an 80-year-old subject and represent the average FDG for both men and women. The right side of the plot indicates the FDR-corrected p value for a “dose-effect” test of whether the log of PiB is associated with regional FDG after accounting for age and sex. FDG = [¹⁸F]-fluorodeoxyglucose; FDR = false discovery rate; PiB = Pittsburgh compound B.