Table 1.
n (%) or median (range) | |
---|---|
Age (years) | 49 (39–63) |
Sex (male) | 11 (69%) |
Race | |
White | 8 (50%) |
African-Americans | 7 (44%) |
Asian | 1 (6%) |
Duration of HIV (months) | 105 (33–235) |
Duration of NRTI therapy (months) | 82 (33–216) |
Duration of stavudine therapy (months) | 48 (9–120) |
ALT (U/l) | 47 (30–108) |
Creatinine kinase (U/l) | 126 (33–369) |
Hemoglobin (g/dl) | (12.9–18.6) |
CD4+ cell count (cells/mm3) | 556 (222–1636) |
HIV-1 RNA <50 copies/ml | 13 (81%) |
Antiretrovirals used at study entry | |
Stavudine | 16 (100%) |
Lamivudine | 10 (62.5%) |
Abacavir | 2 (12.5%) |
Tenofovir | 2 (12.5%) |
PI | 8 (50%) |
NNRTI | 9 (56%) |
Enfuvirtide | 1 (6%) |
Abbreviations: ALT, alanine aminotransferase; HIV-1, human immunodeficiency- 1; NNRTI, non-nucleoside reverse transcriptase inhibitor, NRTI, nucleoside reverse transcriptase inhibitor.