Table 4.
Outcome of TLE lateralization methods.
| FA in Posteroinferior Cingulum |
FA in Crus of Fornix | Hippocampal MD (mm2 /s) |
Hippocampal Volumetrics (mm3) |
Hippocampal FLIAR Intensity Mean±StD |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No | P MTS |
ECoG | Side | Left | Right | L A T |
Left | Right | L A T |
Left | Right | L A T |
Left | Right | L A T |
Left | Right | L A T |
| 1 | Y | Y | L | 0.412 | 0.453 | L | 0.272 | 0.347 | L | 1.3E-3 | 9.6E-4 | L | 1855.0 | 3578.3 | L | 277.7± 36.0 | 269.4±23.9 | L |
| 2 | Y | N | L | 0.299 | 0.342 | L | 0.232 | 0.296 | L | 1.1E-3 | 9.6E-4 | L | 1434.4 | 2373.0 | L | 218.4±38.4 | 195.0±26.6 | L |
| 3 | Y | Y | L | 0.415 | 0.451 | L | 0.323 | 0.459 | L | 1.3E-3 | 1.0E-3 | L | 2050.0 | 3614.8 | L | 252.2±35.0 | 233.8±25.7 | L |
| 4 | Y | N | L | 0.341 | 0.370 | L | 0.350 | 0.380 | L | 1.4E-3 | 1.1E-3 | L | 1641.5 | 3145.7 | L | 273.9±43.7 | 247.2±34.5 | L |
| 5 | Y | N | L | 0.268 | 0.353 | L | 0.260 | 0.284 | L | 1.6E-3 | 1.1E-3 | L | 1155.7 | 2003.5 | L | 468.6±78.0 | 444.6±57.0 | L |
| 6 | Y | N | L | 0.392 | 0.431 | L | 0.306 | 0.335 | L | 1.3E-3 | 1.1E-3 | L | 1926.8 | 2676.4 | L | 558.1±55.6 | 504.5±44.3 | L |
| 7 | Y | N | L | 0.400 | 0.505 | L | 0.390 | 0.392 | U | 1.2E-3 | 1.1E-3 | L | 1774.1 | 3003.4 | L | 314.2±33.5 | 299.2±26.8 | L |
| 8 | Y | Y | R | 0.370 | 0.292 | R | 0.356 | 0.337 | R | 1.4E-3 | 1.4E-3 | R | 2993.9 | 2390.1 | U | 338.9±27.4 | 347.4±43.5 | R |
| 9 | Y | Y | R | 0.272 | 0.192 | R | 0.276 | 0.176 | R | 9.6E-4 | 1.3E-3 | R | 2456.9 | 773.4 | R | 419.2 ±58.3 | 422.8±84.3 | R |
| 10 | Y | N | R | 0.400 | 0.371 | R | 0.365 | 0.322 | R | 1.0E-3 | 1.3E-3 | R | 2803.5 | 1955.4 | R | 295.0±26.7 | 294.4±42.9 | R |
| 11 | N | N | L | 0.412 | 0.458 | L | 0.332 | 0.351 | L | 1.4E-3 | 1.1E-3 | L | 1361.3 | 2806.5 | L | 212.3±43.2 | 212.4±27.2 | L |
| 12 | N | N | L | 0.307 | 0.380 | L | 0.310 | 0.313 | U | 1.2E-3 | 1.2E-3 | L | 2590.9 | 3370.5 | U | 252.5±27.1 | 238.9±27.9 | U |
| 13 | N | N | L | 0.401 | 0.435 | L | 0.351 | 0.359 | U | 1.1E-3 | 1.0E-3 | L | 1969.1 | 3407.6 | L | 236.1±30.4 | 230.2±27.3 | L |
| 14 | N | N | R | 0.341 | 0.327 | U | 0.342 | 0.319 | R | 1.1E-3 | 1.3E-3 | R | 2842.4 | 1923.8 | R | 196.8±26.8 | 207.0±37.3 | R |
| 15 | N | N | R | 0.296 | 0.253 | R | 0.292 | 0.099 | R | 1.2E-3 | 1.8E-3 | R | 1492.0 | 847.8 | R | 301.8±26.3 | 315.3±40.1 | R |
| 16 | N | N | R | 0.344 | 0.335 | U | 0.344 | 0.311 | R | 1.1E-3 | 1.1E-3 | R | 3254.3 | 2503.3 | U | 517.7±77.2 | 514.6±54.4 | L |
| 17 | N | Y | R | 0.304 | 0.322 | U | 0.259 | 0.282 | L | 1.2E-3 | 1.3E-3 | R | 1592.8 | 1922.2 | U | 507.9±57.1 | 500.7±68.3 | R |
| 18 | N | Y | R | 0.321 | 0.342 | U | 0.327 | 0.299 | R | 1.1E-3 | 1.1E-3 | U | 2097.8 | 1899.4 | U | 312.5±37.6 | 310.4±39.9 | U |
| 19 | N | N | R | 0.308 | 0.288 | U | 0.300 | 0.285 | U | 1.1E-3 | 1.1E-3 | U | 3001.8 | 3068.2 | U | 415.6±30.9 | 412.7±35.4 | R |
| 20 | N | Y | R | 0.349 | 0.322 | R | 0.337 | 0.388 | L | 1.1E-3 | 1.2E-3 | R | 2736.6 | 2979.3 | U | 407.7±41.3 | 416.5±35.5 | L |
The side of epileptogenicity is confirmed by postsurgical outcome (Engel classification). Mean FA in the posteroinferior cingulum and fornix crus, and mean hippocampal MD, along with hippocampal volumetrics and mean and standard deviation of FLAIR intensities are shown for left and right hemispheres for each TLE patient with the related putative lateralization of epileptogenicity.
Table notation: P MTS, Pathology-Proven Mesial Temporal sclerosis; StD, Standard Deviation, FA, Fractional Anisotropy; MD, Mean Diffusivity; FLAIR, Fluid Attenuated Inversion Recovery; Side, Side of Epileptogenicity; LAT, Lateralization of Epileptogenicity; Y, Yes; N, No; U, Uncertain Lateralization; L, Left; R, Right.