Table 3. Estimated frequencies of common allele combinations (≥3%) of six examined polymorphisms and their risk prediction for CAD.

Allele combination	All subjects	Patients	Controls	Sim P	OR; 95% CI; P
A-C-C-G-C-G	26.54	25.57	27.36	0.067	Reference
A-C-C-T-C-G	13.62	12.55	14.78	0.520	0.94; 0.67–1.33; 0.735
A-C-C-G-C-A	9.48	10.06	9.38	0.264	1.29; 0.85–1.94; 0.228
A-C-C-T-C-A	7.33	9.32	5.00	<0.001	1.80; 1.19–2.71; 0.005
G-C-T-G-T-G	6.76	6.28	7.13	0.286	0.98; 0.63–1.52; 0.936
G-C-T-G-C-G	6.06	5.56	6.54	0.245	0.92; 0.6–1.41; 0.701
A-C-T-G-C-G	4.41	4.03	5.02	0.019	0.85; 0.51–1.42; 0.544
G-C-T-G-C-A	3.74	3.33	4.44	0.183	0.79; 0.44–1.41; 0.427
G-C-T-T-T-G	3.71	3.93	3.48	0.491	1.92; 1.11–3.30; 0.019
G-C-T-T-C-G	3.64	4.68	2.73	0.085	1.25; 0.71–2.19; 0.433
G-C-T-G-T-A	3.13	2.67	3.18	0.636	0.73; 0.37–1.44; 0.363

Abbreviations: CAD, coronary artery disease; Sim P, simulated P value; OR, odds ratio; 95% CI, 95% confidence interval.