Table 2. Prevalence and levels of antibody responses to PfMSP5 in the three cohorts.
Ab responses against PfMSP5 | |||
Dielmo Year 2002 | Ndiop Year 2002 | Ndiop Year 2000 | |
Mean OD/median-[range] | 0.41/0.32[0.01–1.7] | 0.27/0.16 [0.01–1.46] | 0.38/0.21 [0.01–2.63] |
Mean ODratio/median-[range] | 4.3/3.3 [1–17.1] | 4.3/2.7 [1–22.8] | 3.9/2.4 [1–23.2] |
Prevalence of responders* | 74% | 65% | 60% |
Prevalence in younger individuals** | 79% (n = 19) | 58% (n = 85) | 49% (n = 80) |
Prevalence in older individuals | 74% (n = 167) | 70% (n = 136) | 70% (n = 124) |
*Individuals with positive IgG response = ODratio>2 ie > OD of naive control + 2SD.
**Younger individuals : in Dielmo ie <7 years old; in Ndiop ie <15 years old.