Table 3. Prevalence and levels of antibody responses to PfMSP1p19 in the three cohorts.
Ab responses against PfMSP1p19 | |||
Dielmo Year 2002 | Ndiop Year 2002 | Ndiop Year 2000 | |
Mean OD/median-[range] | 0.79/0.55[0.01–1.7] | 0.86/0.80 [0–1.96] | 0.94/0.79 [0.0–2.69] |
Mean ODratio/median-[range] | 7.9/5.3 [1–16.9] | 6.0/5.5 [1–18.0] | 7.9/6.7 [1–22.7] |
Prevalence of responders* | 73% | 74% | 78% |
Prevalence in younger individuals** | 68% (n = 19) | 60% (n = 85) | 65% (n = 80) |
Prevalence in older inviduals | 74% (n = 167) | 83% (n = 136) | 87% (n = 124) |
*Individuals with positive IgG response = ODratio>2 ie > OD of naive control + 2SD.
**Younger individuals : in Dielmo ie <7 years old; in Ndiop ie <15 years old.