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. 2014 Jul 21;9(7):e103105. doi: 10.1371/journal.pone.0103105

Table 2. Impact of same-day diagnosis on stress and anxiety, measured by the six-item State Trait Anxiety Inventory (STAI).

Mean STAI scores (SE) STAI 1 before intake STAI 2 before imaging STAI 3 before diagnosis STAI 4 1 day after dx STAI 5 3 days after dx STAI 6 7 days after dx Overall P-value*
All patients (n = 127) 45.2 (1.2) 42.9 (1.2) 38.4 (1.2) 32.2 (1.3) 30.7 (1.3) 30.0 (1.5) <0.001
Benign disease (n = 105) 44.4 (1.3) 42.1 (1.3) 36.5 (1.2) 28.2 (1.3) 26.8 (1.3) 25.9 (1.3) <0.001
Malignant disease (n = 22) 48.6 (2.7) 46.4 (2.7) 47.7 (2.7) 48.6 (2.7) 46.6 (2.5) 46.7 (2.2) 0.933
No biopsy performed (n = 76) 45.7 (1.4) 42.8 (1.4) 34.3 (1.4) 26.3 (1.5) 25.3 (1.4) 25.5 (1.5) <0.001
Core needle biopsy performed (n = 51) 44.4 (1.9) 43.0 (1.9) 44.8 (1.9) 40.8 (2.1) 38.5 (2.1) 36.1 (2.3) 0.005
Score CWS <7 (n = 75)a 43.3 (1.6) 41.6 (1.6) 38.8 (1.6) 32.5 (1.7) 31.2 (1.7) 30.2 (1.7) <0.001
Score CWS ≥7 (n = 43) 48.3 (1.8) 45.2 (1.8) 37.7 (1.8) 31.5 (2.0) 29.4 (2.2) 29.5 (2.9) <0.001
Age <65 years (n = 104) 45.1 (1.3) 42.6 (1.3) 37.8 (1.3) 30.8 (1.4) 28.4 (1.4) 28.4 (1.6) <0.001
Age ≥65 years (n = 23) 45.3 (2.6) 44.1 (2.6) 41.4 (2.7) 37.2 (2.7) 38.5 (3.1) 33.9 (3.6) 0.001
No history of breast cancer (n = 120) 45.7 (1.3) 43.0 (1.3) 38.6 (1.3) 32.4 (1.3) 31.0 (1.4) 30.1 (1.6) <0.001
History of breast cancer (n = 7) 36.2 (3.5) 41.4 (3.5) 35.2 (3.5) 28.5 (3.8) 25.8 (3.6) 28.0 (3.6) 0.024
Negative family history (n = 82) 46.5 (1.4) 44.5 (1.4) 39.6 (1.4) 33.1 (1.6) 30.7 (1.7) 30.8 (2.0) <0.001
Positive family history (n = 45) 42.7 (2.2) 40.0 (2.1) 36.3 (2.1) 30.5 (2.3) 30.5 (2.2) 28.4 (2.3) <0.001
Palpable lesion/complaints (n = 79) 44.1 (1.4) 42.0 (1.4) 36.2 (1.4) 28.7 (1.5) 26.9(1.5) 27.2 (1.9) <0.001
Lesions detected by the Screening Program (n = 48) 47.1 (2.1) 44.4 (2.1) 42.1 (2.1) 37.8 (2.2) 37.9 (2.3) 34.6 (2.2) <0.001
Educationb: Low (n = 19) 48.2 (3.1) 46.3 (3.0) 44.6 (3.0) 34.8 (3.2) 33.5 (3.4) 33.4 (4.0) <0.001
Medium (n = 25) 43.0 (2.4) 39.1 (2.4) 34.9 (2.4) 30.9 (2.3) 28.8 (2.3) 26.8 (2.3) <0.001
High (n = 41) 46.5 (2.2) 44.1 (2.2) 40.7 (2.2) 31.8 (2.2) 31.8 (2.1) 30.8 (2.2) <0.001

Abbreviations: STAI, State Trait and Anxiety Scores; SE, Standard Error; dx, diagnosis; CWS, Cancer Worry Scale.

*P-values from mixed model analysis indicating the significance of decrease in anxiety over time.

a

Nine patients did not fill in the cancer worry scale.

b

Level of education was unknown in 42 patients.