Table 3.
Gametocyte risk factors
|
Variables |
Gametocytaemia versus variables |
First event versus variables |
Multiple events versus variables |
|---|---|---|---|
| OR (95% CI) p-value | HR (95% CI) p-value | HR (95% CI) p-value | |
| Age category 2 |
1.05 (1.00, 1.11) 0.036 |
0.44 (0.16, 1.23) 0.118 |
0.63 (0.44, 0.89) 0.01 |
| Age category 3 |
0.36 (0.17, 0.74) 0.005 |
0.75 (0.29, 1.90) 0.54 |
0.76 (0.54, 0.89) 0.01 |
| Bed net use |
0.26 (0.08, 0.91) 0.035 |
1.32 (0.57, 3.05) 0.515 |
1.34 (1.01, 1.80) 0.46 |
| Pf enrolmenta |
4.46 (2.94, 6.74) <0.001 |
3.36 (1.26, 8.98) 0.016 |
3.56 (2.37, 5.37) <0.001 |
| Anaemia |
1.24 (0.82, 1.88) 0.299 |
1.46 (0.55, 3.87) 0.447 |
2.06 (1.49, 2.85) <0.001 |
| Hyper Pfb |
1.44 (1.03, 2.01) 0.034 |
0.86 (0.20, 3.78) 0.845 |
0.34 (0.16, 0.74) 0.007 |
| Pretreatment |
1.81 (1.20, 2.72) 0.004 |
0.85 (0.38, 1.88) 0.682 |
0.81 (0.62, 1.06) 0.128 |
| Mixed Infection | 1.05 (1.00, 1.11) 0.036 | 4.89 (1.99, 11.99) 0.001 | 0.63 (0.44, 0.89) 0.01 |
a Plasmodium falciparum positive participants at enrolment.
bParticipants with hyper parasitaemia which is 100,000 p/mL and above.
Odds ratio (OR), hazardous ratio (HR), the 95% confidence interval (95% CI) and p-values based on Cox regression analysis were generated. Association between gametocytaemia, the time to the first or only episode of gametocytaemia, the risk for multiple events of gametocytaemia, with the variables of interest were determined.