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. 2014 Mar 14;18(4):445–450. doi: 10.1007/s40291-014-0095-2

Table 3.

Stratified analyses between the distribution of CYP1A1 Ile462Val genotypes and cervical cancer risks: pregnancy, oral contraceptive use, tobacco smoking, and menopausal status

High-risk exposure Patients Controls Adjusted OR (95 % CI)a p-Valueb
Genotype Ile/Ile Ile /Val Ile/Ile Ile /Val
Parity
 Ever 370 35 416 23 1.739 (1.006–3.009) 0.0472
 Never 45 6 50 6 1.596 (0.441–5.773) 0.4709
Oral contraceptive use
 Ever 187 21 205 12 1.923 (0.918–4,030) 0.0821
 Never 228 20 261 17 1.370 (0.697–2.692) 0.3597
Smoking
 Ever 134 27 154 10 2.978 (1.382–6.418) 0.0052
 Never 281 14 312 19 1.338 (0.575–3.113) 0.4983
Menopausal status
 Premenopausal 149 10 178 12 0.939 (0.391–2.257) 0.8885
 Postmenopausal 266 31 288 17 1.857 (0.997–3.460) 0.0507

a(Ile /Val vs. Ile/Ile)

bChi square analysis

All p-values were adjusted by age. Significant results are highlighted in bold font

CI confidence interval, OR odds ratio