Table 1.
Family structure of cats analyzed for the PRA locus
| Family no. | Affection | Number of offspring | No. discordant | |||
|---|---|---|---|---|---|---|
| Sire | Dam | Affected | Unaffected | Trios | Sib-pairs | |
| 1 | ∓ | ∓ | 1 | 1 | 1 | 1 |
| 2a | −/− | ∓ | 6 | 4 | 6 | 24 |
| 3a | −/− | ∓ | 2 | 5 | 2 | 10 |
| 4a | −/− | ∓ | 3 | 0 | 3 | 0 |
| 5a | −/− | ∓ | 1 | 2 | 1 | 2 |
| 6a | −/− | ∓ | 6 | 3 | 6 | 18 |
| 7a | ∓ | −/− | 2 | 3 | 2 | 6 |
| 8a | ∓ | −/− | 2 | 6 | 2 | 12 |
| 9a | ∓ | −/− | 1 | 1 | 1 | 1 |
| 10a | ∓ | −/− | 2 | 2 | 2 | 4 |
| 11a | −/− | ∓ | 3 | 0 | 3 | 0 |
| 12a | ∓ | −/− | 1 | 1 | 1 | 1 |
| 13 | ∓ | ∓ | 2 | 1 | 2 | 2 |
| 14a | −/− | +/+ | 0 | 3 | 0 | 0 |
| 15a | +/+ | −/− | 0 | 3 | 0 | 0 |
| 16a | −/− | +/+ | 0 | 3 | 0 | 0 |
| 17a | −/− | +/+ | 0 | 4 | 0 | 0 |
| 18 | +/+ | +/+ | 0 | 1 | 0 | 0 |
| 19 | ∓ | +/+ | 0 | 1 | 0 | 0 |
| 20a | ∓ | −/− | 0 | 1 | 0 | 0 |
| 21a | +/+ | −/− | 0 | 1 | 0 | 0 |
| 22a | ∓ | −/− | 1 | 0 | 1 | 0 |
| 23 | +/+ | +/+ | 0 | 1 | 0 | 0 |
| 24a | +/+ | −/− | 0 | 1 | 0 | 0 |
| 25a | +/+ | −/− | 0 | 1 | 0 | 0 |
| 26 | – | −/− | 2 | 2 | 0 | 4 |
| 27 | – | – | 0 | 2 | 0 | 0 |
| 28 | – | ∓ | 1 | 0 | 0 | 0 |
| 29 | – | ∓ | 0 | 2 | 0 | 0 |
| 30 | – | – | 0 | 2 | 0 | 0 |
| Total |
Unaff. singleton parent = 12 Aff. Singleton parent = 1 |
36 | 57 | 33 | 85 | |
aPhenotypically discordant parent pairs (n = 20). Founders may have been used in more than one family but highlighted once. The first 25 families have two known parents