Table 1.

Study Drugs

Brand name	Generic name	FDA approval date	Manufacturer	Patent expiration
Short-acting beta-agonists
Alupent	Metaproterenol sulfate	01/01/1982	Boehringer Ingelheim	NA
Brethine	Terbutaline sulfate	01/01/1982	Novartis	NA
Maxair	Pirbuterol acetate	12/30/1986	3M	05/12/2004
ProAir HFA	Albuterol	10/29/2004	Teva Global	02/25/2014
Proventil	Albuterol	01/01/1982	Schering	NA
Proventil HFA	Albuterol	08/15/1996	3M	07/06/2010
Ventolin	Albuterol	04/19/2001	GlaxoSmithKline	10/14/2015
Ventolin HFA	Albuterol	04/19/2001	GlaxoSmithKline	10/14/2015
Xopenex	Levalbuterol hydrochloride	03/25/1999	Sepracor	01/05/2010
Xopenex HFA	Levalbuterol tartrate	03/11/2005	Sepracor	07/06/2010
Inhaled corticosteroids
Aerobid	Flunisolide	08/17/1984	Roche Palo	06/12/2007
Asmanex	Mometasone furoate	03/30/2005	Schering	07/27/2014
Azmacort	Triamcinolone acetonide	04/23/1982	Abbott	12/31/2007
Flovent	Fluticasone propionate	05/14/2004	GlaxoSmithKline	08/19/2014
Flovent HFA	Fluticasone propionate	05/14/2004	GlaxoSmithKline	08/19/2014
Pulmicort	Budesonide	06/24/1997	AstraZeneca	08/27/2006
Pulmicort Flexhaler	Budesonide	07/12/2006	AstraZeneca	01/09/2018
Qvar	Beclomethasone dipropionate	09/15/2000	Ivax Res	11/28/2009
Vancenase	Beclomethasone dipropionate	01/01/1982	Schering	12/21/1999
Vanceril	Beclomethasone dipropionate	01/01/1982	Schering	NA
Long-acting beta-agonists
Foradil	Formoterol fumarate	02/16/2001	Novartis	03/08/2019
Serevent	Salmeterol xinafoate	02/04/1994	GlaxoSmithKline	02/12/2008
Inhaled corticosteroid + long-acting beta-agonist combinations
Advair Diskus	Fluticasone propionate + salmeterol xinafoate	08/24/2000	GlaxoSmithKline	08/12/2008
Advair HFA	Fluticasone propionate + salmeterol xinafoate	06/08/2006	GlaxoSmithKline	08/12/2008
Symbicort	Budesonide + formoterol fumarate dihydrate	07/21/2006	AstraZeneca	09/23/2012

FDA indicates US Food and Drug Administration; NA, not applicable.