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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Jul 8;89(5):1106–1114. doi: 10.1016/j.ijrobp.2014.04.012

Fig 1. Loss of NPM1 results in more constitutive and IR-induced γH2AX foci.

Fig 1

NPM1-wt and NPM1-null MEFs were administered 0 or 1 Gy. Irradiated cells were incubated at 37°C for 1 or 6 hrs. Histogram showing the fraction of cells with 11–20 (white bars) or >20 (black bars) γH2AX foci N= 200–250 nuclei per point. *P < 10−3 2 tailed Fisher’s Exact Test.