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. 2014 Jul 12;56(1):42. doi: 10.1186/s13028-014-0042-6

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Copyright © 2014 Stenfeldt et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Histopathological evaluation of myocardium from A) uninfected control pig, B) Case 1, pig that died at 5dpe, FMDV A24 Cruzeiro. Multifocal myocardial necrosis and fragmentation (*) with interstitial edema and mixed mononuclear infiltrates consisting of small mononuclear cells with sparse to modest cytoplasm, large macrophage-like cells, few spindle cells (←) and scarce neutrophils. C) Case 2, Myocardium from pig that died at 3 dpe, FMDV O1 Campos. Multifocal myocardial degeneration and rare necrosis (*) with interstitial edema and cardiomyocyte atrophy and cytoplasmic vacuolization. Mild mixed mononuclear infiltrates consisting of mainly spindle shaped cells with elongated nuclei (←) and small mononuclear cells. Hematoxylin & eosin stain, scale bars = 25 μm.